Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016261 | 1.00 | THRB (0.36) | THRBLMNATSHRMMP8 | |
| SCHEMBL17546640 | 0.73 | — | — | |
| SCHEMBL12057020 | 0.72 | THRB (0.40) | THRBLMNATSHR | |
| SCHEMBL25823909 | 0.72 | THRB (0.40) | THRBLMNATSHR | |
| SCHEMBL62770 | 0.71 | — | — | |
| SCHEMBL11775904 | 0.71 | THRB (0.44) | THRBLMNATSHR | |
| SCHEMBL16382338 | 0.70 | LMNA (0.43) | THRBLMNATSHR | |
| SCHEMBL20731010 | 0.70 | — | — | |
| SCHEMBL28768429 | 0.70 | THRB (0.33) | THRBLMNA | |
| SCHEMBL30990391 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119695-B2 | Compounds and methods for treating breast cancer and other diseases | CITY OF HOPE (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090176305-A1 | COMPOUNDS AND METHODS FOR TREATING BREAST CANCER AND OTHER DISEASES | CITY OF HOPE | 2009-07-09 | — | — | US | disclosed |