Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768429 | 0.85 | THRB (0.33) | THRBLMNA | |
| SCHEMBL4498449 | 0.85 | THRB (0.33) | THRBLMNA | |
| SCHEMBL29343773 | 0.77 | CYP2C19 (0.32) | — | |
| SCHEMBL12057020 | 0.77 | THRB (0.40) | THRBLMNATSHRTDP1 | |
| SCHEMBL24357467 | 0.76 | THRB (0.35) | THRBLMNA | |
| SCHEMBL16382338 | 0.74 | LMNA (0.43) | THRBLMNATSHRTDP1 | |
| SCHEMBL14668867 | 0.72 | THRB (0.36) | THRBLMNA | |
| SCHEMBL10016261 | 0.72 | THRB (0.36) | THRBLMNATSHR | |
| SCHEMBL10048484 | 0.72 | THRB (0.36) | THRBLMNATSHR | |
| SCHEMBL17662678 | 0.71 | LMNA (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |