SCHEMBL10048530

SCHEMBL10048530

CCCC(CO)CCC(CO)CCC(CO)CCCCCCCC(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 3/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP3A4 P08684 1/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PPARG P37231 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
EPHX2 P34913 1/20 0.40
PPARA Q07869 1/20 0.40
PRKCA P17252 1/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCD Q05655 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17526393 0.97 LMNA (0.48) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL17526409 0.97 LMNA (0.48) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL12998128 0.93 LMNA (0.60) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL1457039 0.92 LMNA (0.62) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL2900623 0.92 LMNA (0.62) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL16021262 0.92 LMNA (0.62) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL17526723 0.91 TSHR (0.50) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL17526659 0.91 TSHR (0.50) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL23310433 0.91 TSHR (0.54) LMNAL3MBTL1TSHRMAPTMAPK1
SCHEMBL13443168 0.89 TSHR (0.56) LMNAL3MBTL1TSHRMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927646-B2 Polyurethane dispersion, method of producing the same, coated articles, and method for coating articles DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-06 US disclosed
US-20120053292-A1 POLYURETHANE DISPERSION, METHOD OF PRODUCING THE SAME, COATED ARTICLES, AND METHOD FOR COATING ARTICLES DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 US disclosed
US-20100331559-A1 SEPARATION OF NATURAL OIL-DERIVED ALDEHYDES OR HYDROXY METHYL ESTERS USING PROCESS CHROMATOGRAPHY DOW GLOBAL TECHNOLOGIES INC. (US) 2010-12-30 US disclosed
WO-2009105351-A1 SEPARATION OF NATURAL OIL-DERIVED ALDEHYDES OR HYDROXY METHYL ESTERS USING PROCESS CHROMATOGRAPHY DOW GLOBAL TECHNOLOGIES INC. (US) 2009-08-27 WO disclosed