Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526393 | 1.00 | LMNA (0.48) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL10048530 | 0.97 | LMNA (0.50) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL17526659 | 0.95 | TSHR (0.50) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL17526723 | 0.95 | TSHR (0.50) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL13443168 | 0.93 | TSHR (0.56) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL1457039 | 0.91 | LMNA (0.62) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL16021262 | 0.91 | LMNA (0.62) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL2900623 | 0.91 | LMNA (0.62) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL23310433 | 0.91 | TSHR (0.54) | LMNATSHRL3MBTL1CYP3A4ATM | |
| SCHEMBL12998128 | 0.90 | LMNA (0.60) | LMNATSHRL3MBTL1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | LMNA 3497/4885TSHR 4131/4885L3MBTL1 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.