Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 6/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963836 | 0.90 | BRD4 (0.44) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963816 | 0.87 | GAA (0.45) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963812 | 0.87 | ALDH1A1 (0.53) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963815 | 0.87 | ALDH1A1 (0.53) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963826 | 0.87 | CDK9 (0.48) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963862 | 0.87 | ALDH1A1 (0.47) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963863 | 0.87 | KDM4E (0.47) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963824 | 0.85 | ATM (0.46) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL14963851 | 0.85 | ATM (0.43) | KDM4EGAAALDH1A1CASP1CASP7 | |
| SCHEMBL10048773 | 0.85 | ALDH1A1 (0.51) | KDM4EGAAALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018665-A1 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |