Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 7/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963812 | 0.90 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL14963815 | 0.90 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL10048699 | 0.87 | GAA (0.49) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL14963863 | 0.86 | KDM4E (0.47) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL14963862 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL10048609 | 0.85 | CDK9 (0.53) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL10048727 | 0.85 | KDM4E (0.49) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL14963837 | 0.85 | KDM4E (0.51) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL10048765 | 0.85 | KDM4E (0.47) | ALDH1A1GAAKDM4EHPGDCASP1 | |
| SCHEMBL14963835 | 0.85 | NAMPT (0.49) | ALDH1A1GAAKDM4EHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018665-A1 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |