Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049501 | 0.71 | RAPGEF4 (0.33) | RAPGEF4 | |
| SCHEMBL10049502 | 0.67 | LMNA (0.41) | — | |
| SCHEMBL10049500 | 0.66 | GLA (0.30) | — | |
| SCHEMBL26613397 | 0.56 | ESR1 (0.39) | — | |
| SCHEMBL22075474 | 0.55 | MAPK1 (0.47) | — | |
| SCHEMBL14707142 | 0.54 | CYP2D6 (0.40) | — | |
| SCHEMBL12026633 | 0.54 | CHRNB4 (0.44) | — | |
| SCHEMBL26325595 | 0.53 | RAPGEF4 (0.74) | RAPGEF4 | |
| SCHEMBL19710103 | 0.53 | RAB9A (0.37) | — | |
| SCHEMBL13563418 | 0.53 | SMN1; SMN2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009369-A1 | CATALYSTS BASED ON QUINOLINE PRECURSORS | BASELL POLYOLEFINE GMBG (DE) | 2012-01-19 | — | — | WO | disclosed |