SCHEMBL10049643

SCHEMBL10049643

N#Cc1ccccc1Oc1cc(Cl)ncn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.50
PIN1 Q13526 2/20 0.45
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
ERBB3 P21860 1/20 0.42
ERBB4 Q15303 1/20 0.42
DCK P27707 1/20 0.41
ACHE P22303 1/20 0.41
SLC22A12 Q96S37 1/20 0.39
AR P10275 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
LMNA P02545 2/20 0.37
MAPK14 Q16539 1/20 0.37
ADRB2 P07550 1/20 0.37
SYK P43405 1/20 0.37
GPR119 Q8TDV5 1/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390597 1.00 MAP4K4 (0.50) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL30449029 1.00 MAP4K4 (0.50) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL24507690 0.89 MAP4K4 (0.56) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL7173106 0.85 MAP4K4 (0.50) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL26714156 0.82 POLB (0.54) MAP4K4PIN1GAAPOLBDCK
SCHEMBL7173109 0.82 MAP4K4 (0.50) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL16202033 0.82 MAP4K4 (0.50) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL10073931 0.81 MAP4K4 (0.55) MAP4K4PIN1GAAPOLBEGFR
SCHEMBL7586510 0.81 AR (0.52) MAP4K4GAAPOLBDCKACHE
SCHEMBL7586504 0.81 MAP4K4 (0.49) MAP4K4PIN1GAAPOLBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383864-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF ANHUI GUANGXIN AGROCHEMICAL CO., LTD. (CN) 2024-11-21 US claimed
CN-114957134-B Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2024-07-16 CN claimed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 US claimed
EP-4317137-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF Anhui Guangxin Agrochemical Co., Ltd. (CN) 2024-02-07 EP claimed
WO-2023226456-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF 安徽广信农化股份有限公司 2023-11-30 WO claimed
CN-114957134-A Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2022-08-30 CN claimed
US-20220185784-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL LTD (IN) 2022-06-16 US claimed
EP-3956317-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL Limited (IN) 2022-02-23 EP claimed
CN-113767093-A Process for the preparation of azoxystrobin and intermediates thereof UPL有限公司 2021-12-07 CN claimed
WO-2020212919-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2020-10-22 WO claimed
US-20240383864-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF ANHUI GUANGXIN AGROCHEMICAL CO., LTD. (CN) 2024-11-21 US disclosed
CN-114957134-B Method for preparing azoxystrobin and intermediate thereof 安徽广信农化股份有限公司 2024-07-16 CN disclosed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 US disclosed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 US disclosed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 US disclosed
US-20100036124-A1 PREPARATION OF AZOXYSTROBIN SYNGENTA LIMITED (GB) 2010-02-11 US disclosed
US-20100036124-A1 PREPARATION OF AZOXYSTROBIN SYNGENTA LIMITED (GB) 2010-02-11 US disclosed
US-20080214587-A1 Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes SYNGENTA CROP PROTECTION, INC. (US) 2008-09-04 US disclosed
US-20080214587-A1 Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes SYNGENTA CROP PROTECTION, INC. (US) 2008-09-04 US disclosed
US-20080146571-A1 O-LINKED PYRIMIDIN-4-AMINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE TO TREAT CANCER OXFORD FINANCE LLC, AS COLLATERAL AGENT 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100036124-A1 PREPARATION OF AZOXYSTROBIN CYP51A1, CYP1B1, CYP2D6 MAP4K4 3132/4885PIN1 319/4885GAA 642/4885
US-20240383864-A1 METHOD FOR PREPARING AZOXYSTROBIN AND INTERMEDIATE THEREOF DNMT3L, AZI2, DNMT3A MAP4K4 1836/4885PIN1 215/4885GAA 2626/4885
US-20080214587-A1 Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes DDT, AOC3, DAO MAP4K4 786/4885PIN1 1553/4885GAA 2577/4885
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof NISCH, STS, SNX2 MAP4K4 3099/4885PIN1 1514/4885GAA 541/4885
US-20220185784-A1 PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF NISCH, STS, SNX2 MAP4K4 3099/4885PIN1 1514/4885GAA 541/4885
US-20080146571-A1 O-LINKED PYRIMIDIN-4-AMINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE TO TREAT CANCER DPYD, DHFR, TYMP MAP4K4 2505/4885PIN1 2516/4885GAA 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.