Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.36 |
| ▸ | FABP7 | O15540 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24448592 | 0.88 | KMT2A (0.36) | KMT2AFABP5FABP7EPHX2CASP3 | |
| SCHEMBL10076575 | 0.83 | CASP3 (0.41) | KMT2AEPHX2CASP3PIN1 | |
| SCHEMBL13007532 | 0.79 | HTR2A (0.34) | — | |
| SCHEMBL18949190 | 0.79 | HTR2A (0.31) | CA1CA2 | |
| SCHEMBL29608029 | 0.77 | KMT2A (0.55) | KMT2APOLBFABP5FABP7EPHX2 | |
| SCHEMBL410205 | 0.77 | KMT2A (0.55) | KMT2APOLBFABP5FABP7EPHX2 | |
| SCHEMBL13715647 | 0.76 | HTR2A (0.34) | — | |
| SCHEMBL26761659 | 0.76 | MDM4 (0.38) | CASP3 | |
| SCHEMBL22995984 | 0.76 | KMT2A (0.36) | KMT2AEPHX2 | |
| SCHEMBL27256575 | 0.76 | MDM4 (0.42) | CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536700-A1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATES | Ambrx, Inc. (US) | 2019-09-11 | — | — | EP | disclosed |
| WO-2017161325-A1 | METHODS FOR IDENTIFYING AND MODULATING CO-OCCURANT CELLULAR PHENOTYPES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-09-21 | — | — | WO | disclosed |
| EP-1926757-B1 | ANTIBODY-COMB POLYMER CONJUGATE | UCB PHARMA SA (BE) | 2012-02-22 | — | — | EP | disclosed |