Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24448592 | 0.86 | KMT2A (0.36) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL10051474 | 0.83 | KMT2A (0.37) | CASP3KMT2APIN1EPHX2 | |
| SCHEMBL23395771 | 0.83 | CASP3 (0.40) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL24633696 | 0.83 | MDM4 (0.46) | CASP3MDM4TP53 | |
| SCHEMBL27256575 | 0.82 | MDM4 (0.42) | CASP3MDM4TP53 | |
| SCHEMBL26761659 | 0.82 | MDM4 (0.38) | CASP3MDM4TP53 | |
| SCHEMBL21895802 | 0.82 | TLR2 (0.45) | CASP3MDM4TP53 | |
| SCHEMBL23935524 | 0.82 | MDM4 (0.41) | CASP3MDM4TP53 | |
| SCHEMBL19944058 | 0.82 | MDM4 (0.41) | MDM4TP53 | |
| SCHEMBL729362 | 0.81 | MDM4 (0.35) | CASP3KMT2APIN1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418213-A1 | NEUROMEDIN U DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-02-15 | — | — | EP | disclosed |