SCHEMBL10052128

SCHEMBL10052128

COC(=O)OCC1(C)CCC2CCCC2C1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
CYP19A1 P11511 1/20 0.36
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10448227 0.75 ATP1A1 (0.32)
SCHEMBL12256024 0.74 HMGCR (0.37) CYP19A1
SCHEMBL10447665 0.69 ATP1A1 (0.31)
SCHEMBL14027147 0.68 CYP19A1 (0.39) CYP19A1
SCHEMBL10052131 0.67 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL18708554 0.66 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL13896533 0.66 EPHX1 (0.41) SMN1; SMN2TSHR
SCHEMBL25382656 0.65 ALDH1A1 (0.36) TSHR
SCHEMBL15486282 0.65 ALDH1A1 (0.36)
SCHEMBL15487498 0.64 ALDH1A1 (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331596-B1 TCD BASED HYDROPHILIC POLYURETHANE DISPERSIONS BAYER MATERIALSCIENCE AG (DE) 2012-02-22 EP disclosed