Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754043 | 0.86 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2SENP8SENP7SENP6 | |
| SCHEMBL10052165 | 0.83 | KMT2A (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL24696014 | 0.81 | ATP4A (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1SLC6A3 | |
| SCHEMBL12591884 | 0.80 | CYP19A1 (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL24696020 | 0.80 | HSD17B10 (0.60) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL12591900 | 0.80 | MPL (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1SLC6A3 | |
| SCHEMBL2752581 | 0.79 | MAPT (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1SLC6A3 | |
| SCHEMBL10052158 | 0.79 | MAPT (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL10094543 | 0.78 | CYP19A1 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL13475977 | 0.77 | GRM5 (0.54) | RAB9ASMN1; SMN2CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009141-A1 | FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS | PHARMASCIENCE INC. (CA) | 2012-01-12 | — | — | US | disclosed |
| US-20120009141-A1 | FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS | PHARMASCIENCE INC. (CA) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009141-A1 | FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS | BIRC5, BIRC7, BIRC2 | RAB9A 1245/4885SMN1; SMN2 1759/4885CASP3 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.