Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.51 |
| ▸ | ATP4B | P51164 | 3/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | MRE11 | P49959 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274836 | 0.82 | CYP1A2 (0.41) | ATP4AATP4BPIK3CDPIK3CAPIK3CB | |
| SCHEMBL12591884 | 0.81 | CYP19A1 (0.53) | ATP4AATP4BTLR7MAPTKMT2A | |
| SCHEMBL12591900 | 0.81 | MPL (0.60) | PDE3BPDE3AIDO1SLC6A3TLR7 | |
| SCHEMBL24696020 | 0.81 | HSD17B10 (0.60) | ATP4AATP4BPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10052161 | 0.81 | RAB9A (0.44) | SLC6A3TLR7MAPTKMT2AMEN1 | |
| SCHEMBL18997958 | 0.80 | MEN1 (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL24696015 | 0.80 | MAPT (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGMAPT | |
| SCHEMBL2752581 | 0.80 | MAPT (0.46) | SLC6A3TLR7MAPTKMT2AMEN1 | |
| SCHEMBL10094543 | 0.79 | CYP19A1 (0.57) | ATP4AATP4BC1SMETAP2MAPT | |
| SCHEMBL668132 | 0.79 | ATP4A (0.55) | ATP4AATP4BC1SMRE11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256419-A1 | DUAL WNT SIGNALING PATHWAY INHIBITORS AND AMPK ACTIVATORS FOR TREATMENTS OF DISEASE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-12-08 | — | — | WO | disclosed |