Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052241 | 0.86 | TLR7 (0.47) | TLR7ALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL10052157 | 0.86 | TLR7 (0.56) | TLR7ALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL27830319 | 0.83 | TLR7 (0.54) | TLR7SMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13827949 | 0.74 | TLR7 (0.53) | TLR7SMN1; SMN2NPC1RAB9APIK3CD | |
| SCHEMBL314037 | 0.74 | TLR7 (0.53) | TLR7ALDH1A1POLBPIK3CDPIK3CA | |
| SCHEMBL5520265 | 0.73 | TLR7 (0.51) | TLR7LMNASMN1; SMN2PIK3CDPIK3CA | |
| SCHEMBL21448923 | 0.73 | TLR7 (0.55) | TLR7ALDH1A1SMN1; SMN2PIK3CDPIK3CA | |
| SCHEMBL7029471 | 0.73 | TLR7 (0.51) | TLR7SMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL5512650 | 0.71 | TLR7 (0.50) | TLR7ALDH1A1SMN1; SMN2PIK3CDPIK3CA | |
| SCHEMBL786666 | 0.71 | ALDH1A1 (0.62) | TLR7ALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009141-A1 | FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS | PHARMASCIENCE INC. (CA) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009141-A1 | FUNCTIONALIZED PYRROLIDINES AND USE THEREOF AS IAP INHIBITORS | BIRC5, BIRC7, BIRC2 | TLR7 3296/4885ALDH1A1 4182/4885LMNA 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.