Sugi Predict

Sugi Predict / Compounds / SCHEMBL10052463

SCHEMBL10052463

SCHEMBL10052463

Cc1ccc2c(c1)c1ccccc1n2-c1nc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ ADORA3 P0DMS8 2/20 0.40
▸ NLRP3 Q96P20 1/20 0.40
▸ MAPT P10636 4/20 0.40
▸ ABCG2 Q9UNQ0 2/20 0.40
▸ ADORA2A P29274 1/20 0.40
▸ ADORA1 P30542 1/20 0.40
▸ ABCB1 P08183 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ LMNA P02545 3/20 0.40
▸ TP53 P04637 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ CYP1A1 P04798 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP1B1 Q16678 1/20 0.39
▸ NR1I3 Q14994 1/20 0.39
▸ BCHE P06276 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25661986 0.92 NLRP3 (0.43) L3MBTL1MEN1KMT2AADORA3NLRP3
SCHEMBL19726506 0.92 L3MBTL1 (0.45) L3MBTL1MEN1KMT2AADORA3NLRP3
SCHEMBL10052464 0.91 L3MBTL1 (0.43) L3MBTL1MEN1KMT2AADORA3NLRP3
SCHEMBL30118239 0.91 L3MBTL1 (0.43) L3MBTL1MEN1KMT2AADORA3NLRP3
SCHEMBL16726731 0.91 L3MBTL1 (0.44) L3MBTL1MEN1KMT2ALMNAALDH1A1
SCHEMBL883421 0.91 L3MBTL1 (0.44) L3MBTL1MEN1KMT2AADORA3NLRP3
SCHEMBL16726742 0.91 L3MBTL1 (0.44) L3MBTL1MEN1KMT2ALMNAALDH1A1
SCHEMBL24839334 0.90 MEN1 (0.37) L3MBTL1MEN1KMT2AADORA3NLRP3
SCHEMBL23373492 0.90 NR1I3 (0.41) MEN1KMT2AADORA3NLRP3MAPT
SCHEMBL24657742 0.89 CYP1A1 (0.49) L3MBTL1MEN1KMT2AADORA3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 — — US disclosed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 — — US disclosed
EP-3615542-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-08-23 — — EP disclosed
EP-3573985-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-01-18 — — EP disclosed
WO-2020109524-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-06-04 — — WO disclosed
US-20190280218-A1 SUBSTITUTED OXEPINES MERCK PATENT GMBH (DE) 2019-09-12 — — US disclosed
US-10374170-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2019-08-06 — — US disclosed
EP-2673249-B1 SUBSTITUTED DIBENZONAPHTHACENE MERCK PATENT GMBH (DE) 2019-04-03 — — EP disclosed
WO-2018138306-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-08-02 — — WO disclosed
US-10008675-B2 Organic compound and organic electroluminescent element comprising same DOOSAN CORPORATION (KR) 2018-06-26 — — US disclosed
US-8906893-B2 Substituted tetraarylbenzenes MERCK PATENT GMBH (DE) 2014-12-09 — — US disclosed
US-8906893-B2 Substituted tetraarylbenzenes MERCK PATENT GMBH (DE) 2014-12-09 — — US disclosed
WO-2014098455-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-06-26 — — WO disclosed
WO-2014098447-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-06-26 — — WO disclosed
WO-2014025114-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2014-02-13 — — WO disclosed
US-20130261708-A1 SUBSTITUTED TETRAARYLBENZENES MERCK PATENT GMBH (DE) 2013-10-03 — — US disclosed
US-20130261708-A1 SUBSTITUTED TETRAARYLBENZENES MERCK PATENT GMBH (DE) 2013-10-03 — — US disclosed
US-20120235123-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-09-20 — — US disclosed
WO-2012107163-A1 SUBSTITUTED DIBENZONAPHTHACENE MERCK PATENT GMBH (DE) 2012-08-16 — — WO disclosed
WO-2012079678-A1 SUBSTITUTED TETRAARYLBENZENES MERCK PATENT GMBH (DE) 2012-06-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917913-B2 Substituted oxepines OXGR1, OXTR, OCIAD2 L3MBTL1 1480/4885MEN1 2568/4885KMT2A 1267/4885
US-20120235123-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME OCIAD1, OCIAD2, ODC1 L3MBTL1 858/4885MEN1 2625/4885KMT2A 2850/4885
US-10008675-B2 Organic compound and organic electroluminescent element comprising same OR10J3, ORAI2, ETV6 L3MBTL1 948/4885MEN1 2331/4885KMT2A 1517/4885
US-10374170-B2 Substituted oxepines OXGR1, OXTR, OCIAD2 L3MBTL1 1480/4885MEN1 2568/4885KMT2A 1267/4885
US-20190280218-A1 SUBSTITUTED OXEPINES OXGR1, OXTR, OCIAD2 L3MBTL1 1480/4885MEN1 2568/4885KMT2A 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback