Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.43 |
| ▸ | BHMT | Q93088 | 2/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987066 | 1.00 | LMNA (0.48) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL23398226 | 0.93 | TET2 (0.44) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL10052699 | 0.93 | TET2 (0.44) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL31363055 | 0.84 | TSHR (0.60) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL4657298 | 0.84 | TSHR (0.60) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL11096345 | 0.84 | TSHR (0.60) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL527023 | 0.84 | TSHR (0.60) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL261624 | 0.84 | TET2 (0.54) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL2928385 | 0.84 | TET2 (0.54) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL11618406 | 0.82 | TSHR (0.57) | LMNAFFAR4FFAR1TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028320-A1 | PREPARATION OF ADIPIC ACID | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | disclosed |