Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053367 | 0.94 | HTR1A (0.60) | HTR1ADRD2TSHRABCB11TP53 | |
| SCHEMBL10021781 | 0.93 | HTR1A (0.58) | HTR1ADRD2TSHRCYP3A4CYP2D6 | |
| SCHEMBL10021782 | 0.89 | HTR1A (0.55) | HTR1ADRD2TSHRALDH1A1POLB | |
| SCHEMBL10021765 | 0.86 | TSHR (0.56) | HTR1ADRD2TSHRCYP3A4CYP2D6 | |
| Fluanisone SCHEMBL1902027 | 0.85 | HTR1A (0.68) | HTR1ADRD2ALDH1A1POLB | |
| SCHEMBL10052683 | 0.83 | HTR1A (0.67) | HTR1ACYP3A4CYP2D6KDM4E | |
| SCHEMBL10021766 | 0.82 | TSHR (0.54) | HTR1ADRD2TSHRCYP3A4CYP2D6 | |
| Haloperidol SCHEMBL17962743 | 0.81 | DRD2 (0.61) | HTR1ADRD2TSHRABCB11TP53 | |
| SCHEMBL7427608 | 0.81 | HTR1A (0.71) | HTR1A | |
| Oxalic Acid SCHEMBL4739725 | 0.80 | HTR1A (0.67) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016124-A1 | SEROTONIN REUPTAKE INHIBITORS | BAYLOR UNIVERSITY (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016124-A1 | SEROTONIN REUPTAKE INHIBITORS | HTR2A, HTR2C, HTR1A | HTR1A 3/4885DRD2 54/4885TSHR 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.