Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 10/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4739539 | 0.99 | HTR1A (0.66) | HTR1AHRH3SLC6A4SLC6A9CCR2 | |
| Oxalic Acid SCHEMBL4784368 | 0.92 | HTR1A (0.61) | HTR1AHRH3SLC6A4SLC6A9CCR2 | |
| Oxalic Acid SCHEMBL4785219 | 0.90 | HTR1A (0.67) | HTR1AHRH3SLC6A4SLC6A9 | |
| Oxalic Acid SCHEMBL7437107 | 0.89 | SLC6A4 (0.56) | HTR1AHRH3SLC6A4SLC6A9SLC6A2 | |
| SCHEMBL7430403 | 0.83 | SLC6A4 (0.57) | HTR1AHRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7434240 | 0.83 | SLC6A4 (0.61) | HTR1AHRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7435355 | 0.81 | HRH3 (0.57) | HTR1AHRH3SLC6A4 | |
| Oxalic Acid SCHEMBL4736867 | 0.81 | SLC6A9 (0.51) | HTR1AHRH3SLC6A4SLC6A9 | |
| SCHEMBL7435052 | 0.80 | HRH3 (0.62) | HTR1AHRH3SLC6A4 | |
| SCHEMBL10053313 | 0.80 | HTR1A (0.69) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |