Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005733 | 0.81 | PTPRC (0.44) | LMNAMAPTHTTHPGDALDH1A1 | |
| SCHEMBL15334547 | 0.79 | KMT2A (0.43) | LMNAMAPTHTTHPGDALDH1A1 | |
| SCHEMBL16473372 | 0.76 | KMT2A (0.44) | LMNAMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL921332 | 0.70 | ALDH1A1 (0.53) | LMNAMAPTHTTHPGDALDH1A1 | |
| SCHEMBL478673 | 0.70 | TSHR (0.48) | LMNAMAPTHTTHPGDALDH1A1 | |
| O-Xylene SCHEMBL28327616 | 0.68 | ALDH1A1 (0.38) | LMNAMAPTHTTALDH1A1KDM4E | |
| SCHEMBL921266 | 0.67 | ALDH1A1 (0.57) | LMNAMAPTHTTHPGDALDH1A1 | |
| SCHEMBL1675990 | 0.67 | EGFR (0.56) | MAPTGAAKMT2ATSHRPOLB | |
| SCHEMBL8851854 | 0.67 | ALDH1A1 (0.50) | LMNAMAPTHTTALDH1A1L3MBTL1 | |
| SCHEMBL31538857 | 0.66 | KMT2A (0.46) | LMNAMAPTHPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987495-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987495-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987495-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-03-24 | — | — | US | disclosed |
| EP-2269979-B1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2269979-B1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-04-16 | — | — | EP | disclosed |
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-8563765-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8563765-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8563765-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-24 | — | — | US | disclosed |
| EP-2269979-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | Japan Science and Technology Agency (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-2269979-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | Japan Science and Technology Agency (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | DAO, DDC, DCTD | LMNA 2459/4885MAPT 1399/4885HTT 2562/4885 |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | DAO, DDC, DCTD | LMNA 2459/4885MAPT 1399/4885HTT 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.