SCHEMBL1005343

SCHEMBL1005343

CC(Br)C(=O)OCC1CO1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
MGLL Q99685 2/20 0.37
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92977 0.83 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4MGLL
SCHEMBL16687820 0.83 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4MGLL
SCHEMBL6972562 0.82 LMNA (0.58) ALDH1A1LMNAPOLB
SCHEMBL5247142 0.82 ALDH1A1 (0.53) ALDH1A1TP53CYP3A4MGLL
SCHEMBL4310725 0.81 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4
SCHEMBL25268181 0.80 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLL
SCHEMBL12897815 0.80 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLL
SCHEMBL22689592 0.80 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLL
SCHEMBL14198750 0.80 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLL
SCHEMBL17599522 0.80 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150203639-A1 POLYTHIOPHENE STAR COPOLYMER CAPABLE OF BEING SELF-DOPED BY EXTERNAL STIMULUS, A METHOD FOR PRODUCING THE SAME, A CONDUCTIVE THIN FILM USING THE SAME, AND A METHOD FOR PRODUCING THE CONDUCTIVE THIN FILM KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-07-23 US claimed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
WO-2024146878-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING BAUSCH + LOMB IRELAND LIMITED (IE) 2024-07-11 WO disclosed
WO-2020235442-A1 GRAFT COPOLYMER AND METHOD FOR PRODUCING SAME, AND PRECURSOR FOR GRAFT COPOLYMER 住友精化株式会社 (JP) 2020-11-26 WO disclosed
US-9908979-B2 Polythiophene star copolymer capable of being self-doped by external stimulus, a method for producing the same, a conductive thin film using the same, and a method for producing the conductive thin film KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-06 US disclosed
US-9874566-B2 Compositions and methods for making and using oxygen sensing nanofibers and scaffolds UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2018-01-23 US disclosed
US-20160146974-A1 REDOX PROCESSES FOR CONTACT LENS MODIFICATION TELEFLEX LIFE SCIENCES LIMITED (MT) 2016-05-26 US disclosed
US-20160041177-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS Univ Virginia Patent Found (US) 2016-02-11 US disclosed
US-9120119-B2 Redox processes for contact lens modification SEMPRUS BIOSCIENCES CORPORATION (US) 2015-09-01 US disclosed
US-20150203639-A1 POLYTHIOPHENE STAR COPOLYMER CAPABLE OF BEING SELF-DOPED BY EXTERNAL STIMULUS, A METHOD FOR PRODUCING THE SAME, A CONDUCTIVE THIN FILM USING THE SAME, AND A METHOD FOR PRODUCING THE CONDUCTIVE THIN FILM KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-07-23 US disclosed
WO-2007143209-A2 LUMINESCENT DIKETONATE POLYMERS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2007-12-13 WO disclosed
US-20060258826-A1 Atom or group transfer radical polymerization CARNEGIE MELLON UNIVERSITY 2006-11-16 US disclosed
EP-0966489-B1 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION UNIV CARNEGIE MELLON (US) 2006-11-15 EP disclosed
US-7125938-B2 Atom or group transfer radical polymerization CARNEGIE MELLON UNIVERSITY (US) 2006-10-24 US disclosed
US-20040204556-A1 Atom or group transfer radical polymerization MATYJASZEWSKI KRZYSZTOF (US) 2004-10-14 US disclosed
US-6541580-B1 Controlling living polymerization via e.g. polyphosphazene initiators CARNEGIE MELLON UNIVERSITY 2003-04-01 US disclosed
US-6512060-B1 Contacting at least one first molecule comprising one or more radically transferable atoms or groups, and at least one second molecule comprising one or more radically transferable atoms or groups with a system comprising: a transition metal, CARNEGIE MELLON UNIVERSITY 2003-01-28 US disclosed
EP-0966489-A4 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION UNIV CARNEGIE MELLON (US) 2002-03-06 EP disclosed
EP-0966489-A1 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 1999-12-29 EP disclosed
WO-1998040415-A1 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 1998-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160041177-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS ILK, HIF1A, TNNI3 ALDH1A1 1761/4885TP53 3443/4885CYP3A4 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.