SCHEMBL10053535

SCHEMBL10053535

Cc1ccc(N(c2ccc3ccccc3c2)c2ccc3ccc4cccc5ccc2c3c45)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP3A4 P08684 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 3/20 0.41
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 7/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12856443 0.97 L3MBTL1 (0.44) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL9429272 0.91 ALDH1A1 (0.43) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL460778 0.91 ALDH1A1 (0.48) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL21979757 0.91 CYP1A2 (0.46) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL9237627 0.90 ALDH1A1 (0.42) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL8927497 0.90 ALDH1A1 (0.44) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL10128558 0.90 CYP1A2 (0.42) L3MBTL1ALDH1A1HPGDHSD17B10CYP3A4
SCHEMBL22256082 0.89 L3MBTL1 (0.39) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL13333766 0.89 CYP1A2 (0.42) L3MBTL1HTTNPSR1ALDH1A1HPGD
SCHEMBL9238715 0.88 ALDH1A1 (0.48) L3MBTL1HTTNPSR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2469341-B1 Image bearing member and image forming method, image forming apparatus, and process cartridge RICOH CO LTD (JP) 2016-03-30 EP disclosed
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 US disclosed
US-8652717-B2 Image bearing member and image forming method, image forming apparatus, and process cartridge using the same RICOH COMPANY, LTD. (JP) 2014-02-18 US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-20120163860-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-06-28 US disclosed
EP-2469341-A1 Image bearing member and image forming method, image forming apparatus, and process cartridge Ricoh Company, Ltd. (JP) 2012-06-27 EP disclosed