SCHEMBL460778

SCHEMBL460778

Cc1ccc(N(c2ccc(C)cc2)c2ccc3ccc4cccc5ccc2c3c45)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HPGD P15428 4/20 0.48
HSD17B10 Q99714 3/20 0.48
TSHR P16473 3/20 0.48
CYP3A4 P08684 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP1A2 P05177 5/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
THRB P10828 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
CYP2A6 P11509 2/20 0.35
GUSB P08236 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238715 0.97 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL13152273 0.95 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL14570744 0.95 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL8927497 0.95 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL9429272 0.94 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL29907927 0.93 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL4251786 0.93 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL9749755 0.93 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL2620619 0.93 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL8723948 0.92 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3285960-A None JP disclosed
US-11785846-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-10 US disclosed
US-11785846-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-10 US disclosed
US-20230180604-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-06-08 US disclosed
US-20230180604-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-06-08 US disclosed
US-11588112-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
US-20220209137-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-06-30 US disclosed
US-20220140247-A1 PLURALITY OF HOST MATERIALS, COMPOSITION COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-05 US disclosed
US-11322692-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-05-03 US disclosed
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-02-03 US disclosed
CN-1159613-A Electric photography photoactive elements, processing-box and electric photography apparatus CANON KK (JP) 1997-09-17 CN disclosed
EP-0743561-A2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 1996-11-20 EP disclosed
US-5550293-A CHARGE TRANSFER COMPOUNDS RICOH COMPANY, LTD. (JP) 1996-08-27 US disclosed
US-5488164-A CHARGE GENERATING MATERIAL AND CHARGE TRANSPORT MATERIALS FOR IMAGES RICOH COMPANY, LTD. (JP) 1996-01-30 US disclosed
US-5411828-A Azo dye CANON KABUSHIKI KAISHA (JP) 1995-05-02 US disclosed
US-5382692-A Electrophotographic photoconductors and tertiary amine compounds having condensed polycyclic group for use in the same RICOH COMPANY, LTD. (JP) 1995-01-17 US disclosed
US-5356746-A Containing triazine compound CANON KABUSHIKI KAISHA (JP) 1994-10-18 US disclosed
US-5219692-A Electrophotographic photoconductors and tertiary amine compounds having condensed polycyclic group for use in the same RICOH COMPANY, LTD. (JP) 1993-06-15 US disclosed
EP-0538112-A1 Electrophotographic photosensitive member, electrophotographic apparatus, device unit and facsimile machine CANON KABUSHIKI KAISHA (JP) 1993-04-21 EP disclosed
JP-H03285960-A TERTIARY AMINE COMPOUND HAVING CONDENSED POLYCYCLIC GROUP RICOH CO LTD 1991-12-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11322692-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ICOSLG, ELAVL1, SOD1 ALDH1A1 916/4885HPGD 3897/4885HSD17B10 2879/4885
US-20220037596-A1 PLURALITY OF LIGHT-EMITTING MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, EML4, NECTIN4 ALDH1A1 325/4885HPGD 4605/4885HSD17B10 4582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.