Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649845 | 1.00 | PDK2 (0.40) | PDK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL12864302 | 0.92 | PDK2 (0.46) | PDK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL2606090 | 0.88 | PDK2 (0.33) | PDK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL2606066 | 0.88 | PDK2 (0.41) | PDK2ATMTDP1THRBL3MBTL1 | |
| SCHEMBL2606070 | 0.84 | SRD5A2 (0.41) | PDK2MEN1KMT2ALMNARAB9A | |
| SCHEMBL2606064 | 0.84 | PDK2 (0.44) | PDK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL1167840 | 0.83 | TDP1 (0.52) | PDK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL13351678 | 0.83 | RAB9A (0.53) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL2606061 | 0.82 | PDK2 (0.45) | PDK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL2605937 | 0.82 | CHRM5 (0.37) | PDK2MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260023-B1 | FLUORENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2012-04-25 | — | — | EP | disclosed |