SCHEMBL2606066

C=C(c1cccc(-c2ccccc2)c1)c1cc(C(=O)c2cccc(-c3ccccc3)c2)cc(C2(c3cc(C(=C)c4cccc(-c5ccccc5)c4)cc(C(=O)c4cccc(-c5ccccc5)c4)c3)c3ccccc3-c3ccccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	PDK2	Q15119	7/20	0.41

▸	TDP1	Q9NUW8	2/20	0.41

▸	ATM	Q13315	1/20	0.41

▸	L3MBTL1	Q9Y468	1/20	0.41

▸	KMO	O15229	1/20	0.40

▸	HDAC8	Q9BY41	1/20	0.38

▸	ERCC5	P28715	1/20	0.35

▸	FEN1	P39748	1/20	0.35

▸	DHODH	Q02127	1/20	0.35

▸	UCHL5	Q9Y5K5	1/20	0.35

▸	THRB	P10828	1/20	0.35

▸	CNR2	P34972	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12864305	0.92	TDP1 (0.47)	PDK2TDP1ATML3MBTL1KMO
SCHEMBL10053610	0.88	PDK2 (0.40)	PDK2TDP1ATML3MBTL1THRB
SCHEMBL13649845	0.88	PDK2 (0.40)	PDK2TDP1ATML3MBTL1THRB
SCHEMBL2605973	0.85	VNN1 (0.41)	PDK2TDP1ATML3MBTL1CNR2
SCHEMBL21974933	0.84	ATM (0.57)	TDP1ATML3MBTL1KMOHDAC8
SCHEMBL2606061	0.83	PDK2 (0.45)	PDK2TDP1ATML3MBTL1KMO
SCHEMBL2606064	0.82	PDK2 (0.44)	PDK2TDP1ATML3MBTL1KMO
SCHEMBL12864302	0.82	PDK2 (0.46)	PDK2TDP1ATML3MBTL1THRB
SCHEMBL1167840	0.81	TDP1 (0.52)	PDK2TDP1ATML3MBTL1THRB
SCHEMBL2605937	0.80	CHRM5 (0.37)	PDK2TDP1THRBCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2260023-B1	FLUORENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES	MERCK PATENT GMBH (DE)	2012-04-25	—	—	EP	disclosed