Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1005442

CC(C)n1ccn(C(C)C)c1=[Ru+2](=Cc1ccccc1)=c1n(C(C)C)ccn1C(C)C.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HTR2A P28223 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL852831 0.64 KDM4E (0.30) KDM4ENPC1ALDH1A1TP53GLA
Hydrochloric Acid SCHEMBL6398056 0.62
SCHEMBL9444404 0.60 BRD4 (0.47) KDM4ENPC1ALDH1A1RAB9A
Hydrochloric Acid SCHEMBL1007261 0.58 CYP3A4 (0.44) KDM4EGAAHPGD
SCHEMBL1106502 0.58 MAPT (0.38) ALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL315078 0.55 HTR2A (0.41) ALDH1A1L3MBTL1HTR2A
SCHEMBL840559 0.55 PTGS2 (0.34)
SCHEMBL12676170 0.55 KDM4E (0.50) KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL2462906 0.55 HTR2A (0.38) NPC1ALDH1A1TP53L3MBTL1HTR2A
Benzaldehyde SCHEMBL9700513 0.55 ALDH1A1 (0.70) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3159365-B1 CYCLOPENTENE RING-OPENING POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, AND POLYMER CROSSLINKED PRODUCT ZEON CORP (JP) 2025-01-22 EP disclosed
WO-2023189495-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER OBJECT 日本ゼオン株式会社 2023-10-05 WO disclosed
US-11535696-B2 Crosslinkable composition and crosslinked product ZEON CORPORATION (JP) 2022-12-27 US disclosed
US-20220380522-A1 RING-OPENED COPOLYMER ZEON CORPORATION (JP) 2022-12-01 US disclosed
EP-4079781-A1 RING-OPENED COPOLYMER Zeon Corporation (JP) 2022-10-26 EP disclosed
US-11390709-B2 Liquid copolymer formed by ring-opening copolymerization of cyclopentene, crosslinkable composition, and crosslinked rubber object ZEON CORPORATION (JP) 2022-07-19 US disclosed
US-11267956-B2 Rubber composition and rubber crosslinked product ZEON CORPORATION (JP) 2022-03-08 US disclosed
EP-3533829-B1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2021-11-24 EP disclosed
EP-3689938-A1 LIQUID COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOPENTENE, CROSSLINKABLE COMPOSITION, AND CROSSLINKED RUBBER OBJECT Zeon Corporation (JP) 2020-08-05 EP disclosed
US-20200223979-A1 LIQUID COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOPENTENE, CROSSLINKABLE COMPOSITION, AND CROSSLINKED RUBBER OBJECT ZEON CORPORATION (JP) 2020-07-16 US disclosed
EP-1275675-B1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE ZEON CORP (JP) 2005-12-07 EP disclosed
US-6908970-B2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION (JP) 2005-06-21 US disclosed
US-6815516-B2 HEAT RESISTANCE, SOLVENT SOLUBILITY ZEON CORPORATION (JP) 2004-11-09 US disclosed
US-20040152843-A1 Open-ring copolymer, hydrogenated open-ring copolymer, process for production of both, and compositions ZEON CORPORATION (JP) 2004-08-05 US disclosed
EP-1408064-A1 OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS Zeon Corporation (JP) 2004-04-14 EP disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed