SCHEMBL1005556

SCHEMBL1005556

c1ccc2c(c1)oc1c(-c3cc(-c4cccc5c4oc4ccccc45)c4ccc5c(-c6cccc7c6oc6ccccc67)cc(-c6cccc7c6oc6ccccc67)c6ccc3c4c65)cccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.59
PRKDC P78527 5/20 0.47
PIK3CD O00329 1/20 0.43
PIK3CB P42338 1/20 0.43
AHR P35869 3/20 0.42
GGPS1 O95749 1/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HDAC8 Q9BY41 1/20 0.40
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
CDC25C P30307 1/20 0.40
DYRK1A Q13627 1/20 0.39
PTGES2 Q9H7Z7 1/20 0.39
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15497748 0.94 ALOX5 (0.54) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL15446790 0.92 ALOX5 (0.52) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL9920863 0.91 ALOX5 (0.55) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL9920824 0.88 ALOX5 (0.51) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL15497738 0.88 ALOX5 (0.55) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL9920786 0.87 ALOX5 (0.51) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL9920909 0.87 ALOX5 (0.51) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL13872489 0.87 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL10945864 0.87 ALOX5 (0.68) ALOX5PRKDCPIK3CDPIK3CBAHR
SCHEMBL16307763 0.86 ALOX5 (0.56) ALOX5PRKDCPIK3CDPIK3CBAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1621597-B1 1,3,6,8-TETRASUBSTITUTED PYRENE COMPOUNDS, ORGANIC EL DEVICE AND ORGANIC EL DISPLAY UDC IRELAND LTD (IE) 2013-09-18 EP claimed
US-7871711-B2 blue light-emitting layer includes a 1,3,6,8-tetrasubstituted pyrene compounds selected from 1,3,6,8-tetra(4-biphenyl)pyrene, 1,3,6,8-tetra(4-dibenzofuranyl)pyrene, and 1,3,6,8-tetra(4-dibenzothionyl)pyrene; chloro [2,3,7,8,12,13,17,18-octaethylporphrinato] iron (trivalent) as light emitting material FUJIFILM CORPORATION (JP) 2011-01-18 US claimed
US-20070285005-A1 Organic Electroluminescent Element and Organic Electroluminescent Display FUJI PHOTO FILM., LTD. (JP) 2007-12-13 US claimed
EP-1621597-A1 1,3,6,8-TETRASUBSTITUTED PYRENE COMPOUNDS, ORGANIC EL DEVICE AND ORGANIC EL DISPLAY FUJITSU LIMITED (JP) 2006-02-01 EP claimed
US-20050238920-A1 1,3,6,8-Tetrasubstituted pyrene compound, organic electroluminescent element, and organic electroluminescent display FUJITSU LIMITED (JP) 2005-10-27 US claimed
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US disclosed
US-9287507-B2 Organic electroluminescent element, compounds and materials used for the organic electroluminescent element, and light-emitting, display and illuminating devices using the elements UDC Ireland (IE) 2016-03-15 US disclosed
EP-1621597-B1 1,3,6,8-TETRASUBSTITUTED PYRENE COMPOUNDS, ORGANIC EL DEVICE AND ORGANIC EL DISPLAY UDC IRELAND LTD (IE) 2013-09-18 EP disclosed
EP-1621597-B1 1,3,6,8-TETRASUBSTITUTED PYRENE COMPOUNDS, ORGANIC EL DEVICE AND ORGANIC EL DISPLAY UDC IRELAND LTD (IE) 2013-09-18 EP disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-7989644-B2 Electroluminescent device BASF SE (DE) 2011-08-02 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20070285005-A1 Organic Electroluminescent Element and Organic Electroluminescent Display FUJI PHOTO FILM., LTD. (JP) 2007-12-13 US disclosed
US-20070285005-A1 Organic Electroluminescent Element and Organic Electroluminescent Display FUJI PHOTO FILM., LTD. (JP) 2007-12-13 US disclosed
US-20070285005-A1 Organic Electroluminescent Element and Organic Electroluminescent Display FUJI PHOTO FILM., LTD. (JP) 2007-12-13 US disclosed
US-20070141387-A1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20070141387-A1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
EP-1621597-A1 1,3,6,8-TETRASUBSTITUTED PYRENE COMPOUNDS, ORGANIC EL DEVICE AND ORGANIC EL DISPLAY FUJITSU LIMITED (JP) 2006-02-01 EP disclosed
US-20050238920-A1 1,3,6,8-Tetrasubstituted pyrene compound, organic electroluminescent element, and organic electroluminescent display FUJITSU LIMITED (JP) 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT PYM1, CRY1, S100A10 ALOX5 1264/4885PRKDC 4832/4885PIK3CD 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.