Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308553 | 0.97 | CYP2D6 (0.41) | CYP2D6MEN1USP2ALDH1A1PLA2G1B | |
| Hydrochloric Acid SCHEMBL10546112 | 0.95 | CYP2D6 (0.43) | CYP2D6MEN1USP2ALDH1A1PLA2G1B | |
| SCHEMBL3306688 | 0.84 | CYP2D6 (0.38) | CYP2D6MEN1USP2ALDH1A1PLA2G1B | |
| Bromide SCHEMBL1066554 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL3307555 | 0.81 | CTDSP1 (0.39) | CYP2D6 | |
| SCHEMBL2061000 | 0.78 | — | — | |
| SCHEMBL7123064 | 0.78 | TSHR (0.35) | — | |
| Bromide SCHEMBL11693696 | 0.78 | TSHR (0.35) | CYP2D6 | |
| SCHEMBL10771798 | 0.78 | CYP2D6 (0.35) | CYP2D6ALDH1A1 | |
| SCHEMBL3303638 | 0.78 | CYP2D6 (0.35) | CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454327-B1 | COLOR-CHANGING MATERIALS AND MULTIPLE COMPONENT MATERIALS HAVING A COLOR-CHANGING COMPOSITION | KIMBERLY CLARK CO (US) | 2015-04-15 | — | — | EP | claimed |
| US-20080076851-A1 | Hydrophilic surface modification of contact lenses | GOLDBERG EUGENE P | 2008-03-27 | — | — | US | claimed |
| US-9788548-B2 | Synthesis of pure diallyl morpholinium monomers in high yields and using antibacterial effect of their spiro polymers | Tugrul Cem BICAK (TR) | 2017-10-17 | — | — | US | disclosed |
| US-20160286809-A1 | SYNTHESIS OF PURE DIALLYL MORPHOLINIUM MONOMERS IN HIGH YIELDS AND USING ANTIBACTERIAL EFFECT OF THEIR SPIRO POLYMERS | BICAK, Tugrul Cem (TR) | 2016-10-06 | — | — | US | disclosed |
| EP-1326704-B1 | SURFACE-MODIFIED SEMICONDUCTIVE AND METALLIC NANOPARTICLES HAVING ENHANCED DISPERSIBILITY IN AQUEOUS MEDIA | LIFE TECHNOLOGIES CORP (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2015088464-A1 | SYNTHESIS OF PURE DIALLYL MORPHOLINIUM MONOMERS IN HIGH YIELDS AND USING ANTIBACTERIAL EFFECT OF THEIR SPIRO POLYMERS | BICAK TUGRUL CEM (TR) | 2015-06-18 | — | — | WO | disclosed |
| EP-2454327-B1 | COLOR-CHANGING MATERIALS AND MULTIPLE COMPONENT MATERIALS HAVING A COLOR-CHANGING COMPOSITION | KIMBERLY CLARK CO (US) | 2015-04-15 | — | — | EP | disclosed |
| US-8691384-B2 | Metallic nanoparticles having enhanced dispersibility in aqueous media comprising a polymer having alkyl acrylamide side chains | Life Technologies Corporation (US) | 2014-04-08 | — | — | US | disclosed |
| US-8623290-B2 | Color-changing materials and multiple component materials having a color-changing composition | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20120328485-A1 | Color-Changing Materials And Multiple Component Materials Having A Color-Changing Composition | KIMBERLY-CLARK WORLDWIDE, INC. | 2012-12-27 | — | — | US | disclosed |
| US-8273306-B2 | Color-changing materials and multiple component materials having a color-changing composition | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| WO-1996026222-A1 | AGGLOMERATED POLYMER PARTICLES FROM WATER-SWELLABLE POLYMERS, PROCESSES FOR PRODUCING SAID POLYMER PARTICLES AND THE USE OF SAID PARTICLES | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-29 | — | — | WO | disclosed |
| EP-0412388-B1 | Process of preparation of fine particles of polymers in powder form | BASF AG (DE) | 1995-10-04 | — | — | EP | disclosed |
| US-5346986-A | Flocculants, retention and drainage aids | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |
| EP-0528267-A1 | Shock resistance modifying polymers | BASF Aktiengesellschaft (DE) | 1993-02-24 | — | — | EP | disclosed |
| WO-1992013912-A1 | AGGLOMERATED POLYMER PARTICLES PRODUCED FROM FINELY DIVIDED WATER-SOLUBLE OR WATER-SWELLABLE POLYMERISATES | BASF AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |
| EP-0290753-B1 | PROCESS FOR PREPARING POLYMER BEADS FROM WATER-SOLUBLE ETHYLENICALLY UNSATARATED MONOMERS | BASF Aktiengesellschaft (DE) | 1990-12-19 | — | — | EP | disclosed |
| WO-1990011304-A1 | PROCESS FOR REDUCING THE RESIDUAL MONOMER CONTENT OF DIALLYL AMMONIUM SALT POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-04 | — | — | WO | disclosed |
| US-4879361-A | PAPERMAKING, FLOCCULATION, ABSORBTION | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-07 | — | — | US | disclosed |
| EP-0290753-A1 | Process for preparing polymer beads from water-soluble ethylenically unsatarated monomers | BASF Aktiengesellschaft (DE) | 1988-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160286809-A1 | SYNTHESIS OF PURE DIALLYL MORPHOLINIUM MONOMERS IN HIGH YIELDS AND USING ANTIBACTERIAL EFFECT OF THEIR SPIRO POLYMERS | SBDS, UROD, ADSL | CYP2D6 1169/4885MEN1 4367/4885USP2 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.