Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15044232 | 0.88 | CYP2C9 (0.50) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10055303 | 0.88 | CYP2C9 (0.50) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10055215 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10056409 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10057024 | 0.76 | CYP2C9 (0.48) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL10056203 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10056056 | 0.74 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10055308 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL10055187 | 0.72 | L3MBTL1 (0.44) | SMN1; SMN2MEN1KMT2ANPC1HPGD | |
| SCHEMBL10057054 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |