Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056839 | 0.89 | CYP2C9 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10056232 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL10056857 | 0.76 | CYP2C9 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL15044032 | 0.74 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL10055187 | 0.72 | L3MBTL1 (0.44) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL4855884 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL10056203 | 0.70 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10055215 | 0.69 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL10057024 | 0.69 | CYP2C9 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL10055475 | 0.68 | ATM (0.42) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |