Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.46 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.46 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946411 | 0.91 | ALDH1A1 (0.54) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL12766660 | 0.89 | CYP1A1 (0.51) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL8259382 | 0.80 | CES2 (0.54) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL28331909 | 0.80 | CES2 (0.54) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL1119543 | 0.80 | CES2 (0.54) | CES2CES1SRD5A2IDO1ALDH1A1 | |
| SCHEMBL5206631 | 0.80 | CES2 (0.54) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL22244208 | 0.78 | CES2 (0.39) | CES2CES1SRD5A2GSK3BPTPN1 | |
| Hydrochloric Acid SCHEMBL1549707 | 0.78 | PRSS1 (0.54) | CES2CES1IDO1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27491061 | 0.78 | PRSS1 (0.54) | CES2CES1IDO1ALDH1A1HPGD | |
| SCHEMBL4088597 | 0.78 | CES2 (0.64) | CES2CES1SRD5A2GSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987495-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-03-24 | — | — | US | disclosed |
| EP-2269979-B1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2269979-B1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-04-16 | — | — | EP | disclosed |
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-8563765-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8563765-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-24 | — | — | US | disclosed |
| EP-2269979-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | Japan Science and Technology Agency (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-2269979-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | Japan Science and Technology Agency (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | DAO, DDC, DCTD | CES2 3435/4885CES1 4627/4885SRD5A2 3380/4885 |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | DAO, DDC, DCTD | CES2 3435/4885CES1 4627/4885SRD5A2 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.