Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TERT | O14746 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923976 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL11513168 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL23130687 | 0.87 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL14399200 | 0.84 | HPGD (0.63) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL19962917 | 0.81 | CA1 (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL14369937 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL12330807 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL14367687 | 0.79 | TERT (0.48) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL10001928 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1TERTMEN1KMT2A | |
| SCHEMBL15159310 | 0.77 | AR (0.65) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115128-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2012-05-10 | — | — | US | disclosed |
| WO-2010129929-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-11-11 | — | — | WO | disclosed |