Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056890 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7923976 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23130687 | 0.86 | ALDH1A1 (0.65) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14399200 | 0.85 | HPGD (0.63) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL9509102 | 0.81 | MAPT (0.50) | KDM4EALDH1A1LMNATERTKMT2A | |
| SCHEMBL19962917 | 0.80 | CA1 (0.46) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14369937 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14367687 | 0.78 | TERT (0.48) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL10001928 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1TERTKMT2AMEN1 | |
| SCHEMBL30237615 | 0.77 | MAPT (0.61) | KDM4EALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159264-A | Automatic control of azo coupling processes in the manufacture of azo pigments | CIBA-GEIGY CORPORATION (US) | 1979-06-26 | — | — | US | claimed |
| US-4064131-A | Process for the production of 1,2-dihydro-2-oxo-4-methyl-7-acetoacetic acid amido-quinoline | LONZA, LTD. (CH) | 1977-12-20 | — | — | US | claimed |
| US-4159264-A | Automatic control of azo coupling processes in the manufacture of azo pigments | CIBA-GEIGY CORPORATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4064131-A | Process for the production of 1,2-dihydro-2-oxo-4-methyl-7-acetoacetic acid amido-quinoline | LONZA, LTD. (CH) | 1977-12-20 | — | — | US | disclosed |
| US-4064131-A | Process for the production of 1,2-dihydro-2-oxo-4-methyl-7-acetoacetic acid amido-quinoline | LONZA, LTD. (CH) | 1977-12-20 | — | — | US | disclosed |
| US-4064131-A | Process for the production of 1,2-dihydro-2-oxo-4-methyl-7-acetoacetic acid amido-quinoline | LONZA, LTD. (CH) | 1977-12-20 | — | — | US | disclosed |