Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.43 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | HTR1D | P28221 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | HRH2 | P25021 | 5/20 | 0.43 |
| ▸ | DRD1 | P21728 | 5/20 | 0.43 |
| ▸ | DRD5 | P21918 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | HTR2B | P41595 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078310 | 0.85 | OPRL1 (0.49) | OPRM1OPRD1OPRL1OPRK1HTR1A | |
| SCHEMBL3857799 | 0.81 | OPRL1 (0.55) | OPRM1OPRD1OPRL1OPRK1HTR1A | |
| SCHEMBL10057684 | 0.81 | CYP2D6 (0.48) | OPRM1OPRD1OPRL1OPRK1SLC6A2 | |
| SCHEMBL2929705 | 0.79 | OPRL1 (0.53) | OPRM1OPRD1OPRL1OPRK1HTR1A | |
| SCHEMBL10057649 | 0.79 | OPRL1 (0.60) | OPRM1OPRD1OPRL1OPRK1DRD2 | |
| SCHEMBL3860368 | 0.78 | OPRL1 (0.46) | OPRM1OPRD1OPRL1OPRK1HTR1A | |
| SCHEMBL10057650 | 0.77 | OPRL1 (0.63) | OPRM1OPRD1OPRL1OPRK1DRD2 | |
| SCHEMBL10057646 | 0.76 | OPRM1 (0.63) | OPRM1OPRD1OPRL1OPRK1 | |
| SCHEMBL3115638 | 0.76 | RORC (0.41) | OPRM1OPRD1OPRL1OPRK1SLC6A2 | |
| SCHEMBL2268801 | 0.76 | DRD2 (0.51) | OPRM1OPRD1OPRL1OPRK1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148404-B2 | Modulators of CB1 receptors | 7TM PHARMA A/S (DK) | 2012-04-03 | — | — | US | disclosed |
| US-20100144701-A1 | Modulators of CB1 Receptors | 7TM PHARMA A/S (DK) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144701-A1 | Modulators of CB1 Receptors | CNR1, CNR2, GPR6 | OPRM1 81/4885OPRD1 78/4885OPRL1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.