SCHEMBL1005838

SCHEMBL1005838

O=C(Nc1ccc(Oc2ccc(Cl)cc2Cl)cc1)c1cccc2ncoc12

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 15/20 0.56
STK39 Q9UEW8 3/20 0.52
PARG Q86W56 2/20 0.48
KDR P35968 1/20 0.48
GCGR P47871 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12952608 0.86 PNLIP (0.56) PNLIPSTK39PARG
SCHEMBL2781663 0.82 PNLIP (0.54) PNLIPSTK39PARGKDR
SCHEMBL2780259 0.82 PNLIP (0.57) PNLIPSTK39PARGKDR
SCHEMBL2781668 0.82 PNLIP (0.54) PNLIPSTK39PARGKDRGCGR
SCHEMBL905961 0.77 ABL1 (0.49) KDR
SCHEMBL905811 0.76 MAPT (0.52)
SCHEMBL12975008 0.76 PNLIP (0.47) PNLIPSTK39PARGKDR
SCHEMBL2761675 0.76 PNLIP (0.65) PNLIPSTK39PARG
SCHEMBL2762118 0.73 G6PD (0.62) PNLIPSTK39PARG
SCHEMBL23685887 0.72 PNLIP (0.81) PNLIPSTK39PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2277870-A1 Substituted benzoxa(thia)zoles Bayer CropScience AG (DE) 2011-01-26 EP disclosed
WO-2010149310-A1 DI-SUBSTITUTED PHENYLOXY(THIO)PHENYLAMIDE BENZOXA(THIA)ZOLES BAYER CROPSCIENCE AG (DE) 2010-12-29 WO disclosed