SCHEMBL2780259

SCHEMBL2780259

Cc1nc2cccc(C(=O)Nc3ccc(Oc4ccc(Cl)cc4Cl)cc3)c2o1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 13/20 0.57
PARG Q86W56 4/20 0.50
STK39 Q9UEW8 3/20 0.50
KDR P35968 1/20 0.49
CTSD P07339 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781663 0.89 PNLIP (0.54) PNLIPPARGSTK39KDRCTSD
SCHEMBL2781668 0.89 PNLIP (0.54) PNLIPPARGSTK39KDRCTSD
SCHEMBL12975008 0.83 PNLIP (0.47) PNLIPPARGSTK39KDRCTSD
SCHEMBL1005838 0.82 PNLIP (0.56) PNLIPPARGSTK39KDR
SCHEMBL2761675 0.74 PNLIP (0.65) PNLIPPARGSTK39
SCHEMBL15223386 0.71 MEN1 (0.68) PNLIPSTK39
SCHEMBL2762118 0.71 G6PD (0.62) PNLIPPARGSTK39
SCHEMBL12952608 0.71 PNLIP (0.56) PNLIPPARGSTK39
SCHEMBL23685887 0.70 PNLIP (0.81) PNLIPPARGSTK39
SCHEMBL8661386 0.70 GCGR (0.87) PNLIPPARGSTK39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010149310-A1 DI-SUBSTITUTED PHENYLOXY(THIO)PHENYLAMIDE BENZOXA(THIA)ZOLES BAYER CROPSCIENCE AG (DE) 2010-12-29 WO disclosed
WO-2010149310-A1 DI-SUBSTITUTED PHENYLOXY(THIO)PHENYLAMIDE BENZOXA(THIA)ZOLES BAYER CROPSCIENCE AG (DE) 2010-12-29 WO disclosed