SCHEMBL1005855

SCHEMBL1005855

COC(=O)[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27874684 0.97
SCHEMBL2125856 0.74
SCHEMBL25706 0.74 ALDH1A1 (0.44)
SCHEMBL7806775 0.73
SCHEMBL968390 0.71
SCHEMBL15873629 0.71
SCHEMBL1387681 0.71
SCHEMBL5226186 0.71
SCHEMBL28800874 0.69
SCHEMBL166474 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024068520-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO claimed
WO-2024068519-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO claimed
EP-2807170-B1 PHRAGMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION DICOT AB (SE) 2019-03-13 EP claimed
US-20150011616-A1 PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION DICOT PHARMA AB (SE) 2015-01-08 US claimed
EP-2807170-A2 PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION Dicotyledon AB (SE) 2014-12-03 EP claimed
WO-2013110744-A2 NOVEL COMPOUNDS, THEIR MANUFACTURE AND USES (II) DICOTYLEDON AB (SE) 2013-08-01 WO claimed
WO-2008060998-A1 INDOLE SULFONAMIDES AS SFRP-1 MODULATORS WYETH (US) 2008-05-22 WO claimed
EP-1105372-B1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2003-06-11 EP claimed
US-20030069287-A1 Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors PHARMACIA CORPORATION 2003-04-10 US claimed
EP-1288206-A1 Substituted benzenesulfonamide derivatives as prodrugs of COX-2 inhibitors G.D. SEARLE & CO. (US) 2003-03-05 EP claimed
US-5932598-A NOVEL SUBSTITUTED SULFONAMIDE COMPOUNDS USEFUL AS PRODRUGS; ADMINISTERING TO TREAT INFLAMMATION-ASSOCIATED PAIN DUE TO CANCER, DENTAL PAIN; CYCLOOXYGENASE-2 INHIBITORS G. D. SEARLE & CO. (US) 1999-08-03 US claimed
EP-0892791-A1 SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AS PRODRUGS OF COX-2 INHIBITORS G.D. SEARLE & CO. (US) 1999-01-27 EP claimed
US-5716974-A TREATING FUNGAL PLANT DISEASES ISAGRO S.P.A. (IT) 1998-02-10 US claimed
WO-1997038986-A1 SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AS PRODRUGS OF COX-2 INHIBITORS G.D. SEARLE & CO. (US) 1997-10-23 WO claimed
EP-0662477-A1 Heterobicyclic compounds with fungicidal activity ISAGRO S.p.A. (IT) 1995-07-12 EP claimed
EP-0490569-A1 N-aryl-3-aryl-4-substitued-2,3,4,5-tetrahydro-1H-pyrazole-1-carboxamides and methods of their production ROHM AND HAAS COMPANY (US) 1992-06-17 EP claimed
US-5109014-A Useful as insecticide or pesticide DOW AGROSCIENCES LLC, A DELAWARE LIMITED LIABILITY COMPANY 1992-04-28 US claimed
US-5097028-A Herbicides for crops such as wheat, barley, cotton, soybeans BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US claimed
EP-0410238-A2 Pyridazinone derivatives BAYER AG (DE) 1991-01-30 EP claimed
US-4960910-A Intermediates for nucleoside antibiotics NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-10-02 US claimed