⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25706 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL2125856 | 0.74 | — | — | |
| SCHEMBL1387681 | 0.71 | — | — | |
| SCHEMBL15873629 | 0.71 | — | — | |
| SCHEMBL1005855 | 0.71 | — | — | |
| SCHEMBL1387203 | 0.69 | — | — | |
| SCHEMBL2939248 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL1462427 | 0.69 | — | — | |
| SCHEMBL166474 | 0.69 | — | — | |
| SCHEMBL29032093 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565905-A1 | STEPWISE SEQUENCING BY NON-LABELED REVERSIBLE TERMINATORS OR NATURAL NUCLEOTIDES | MGI Tech Co., Ltd. (CN) | 2019-11-13 | — | — | EP | claimed |
| WO-2018129214-A1 | STEPWISE SEQUENCING BY NON-LABELED REVERSIBLE TERMINATORS OR NATURAL NUCLEOTIDES | COMPLETE GENOMICS, INC. (US) | 2018-07-12 | — | — | WO | claimed |
| US-20100227859-A1 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH LLC | 2010-09-09 | — | — | US | claimed |
| EP-2144893-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2010-01-20 | — | — | EP | claimed |
| WO-2008137816-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-11-13 | — | — | WO | claimed |
| WO-2006091905-A1 | BICYCLO (3.1.0) HEXANE DERIVATIVES AS ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-08-31 | — | — | WO | claimed |
| US-6355615-B1 | CYCLIC POLYAMIDEESTER COPOLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | claimed |
| CN-1076349-C | Desoxycyclodepsipeptides and their use for combatting endoparasites | BAYER AG (DE) | 2001-12-19 | — | — | CN | claimed |
| CN-1259129-A | Desoxycyclodepsipeptides and their use for combatting endoparasites | BAYER AG (DE) | 2000-07-05 | — | — | CN | claimed |
| US-6083951-A | FOR THE TREATMENT OF DISEASES OR MEDICAL CONDITIONS SUCH AS HYPERTENSION, PULMONARY HYPERTENSION, CARDIAC OR CEREBRAL CIRCULATORY DISEASE AND RENAL DISEASE | ZENECA LIMITED (GB) | 2000-07-04 | — | — | US | claimed |
| US-5861401-A | TREATMENT OF CONGESTIVE HEART FAILURE | ZENECA LIMITED (GB) | 1999-01-19 | — | — | US | claimed |
| WO-1998055469-A1 | DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-10 | — | — | WO | claimed |
| JP-H09510987-A | — | — | 1997-11-04 | — | — | JP | claimed |
| US-5668137-A | N-heterocyclic sulfonamides having endothelin receptor activity | ZENECA LTD. (GB) | 1997-09-16 | — | — | US | claimed |
| US-5641793-A | POSSESS ENDOTHELIN RECEPTOR ANTAGONIST ACTIVITY; USEFUL IN TREATMENT OF HYPERTENSION, CARDIAC OR CEREBRAL CIRCULATORY DISEASE AND RENAL DISEASE | ZENECA LIMITED (GB) | 1997-06-24 | — | — | US | claimed |
| EP-0752986-A1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1997-01-15 | — | — | EP | claimed |
| EP-0749964-A1 | N-Heterocyclyl biphenyl sulfonamides | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | claimed |
| EP-0682016-A1 | Pyridine derivatives | ZENECA LIMITED (GB) | 1995-11-15 | — | — | EP | claimed |
| WO-1995026957-A1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1995-10-12 | — | — | WO | claimed |
| US-4256752-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-03-17 | — | — | US | claimed |