SCHEMBL10058646

SCHEMBL10058646

CC(CN1CCCC1)(CN1CCCC1)CN1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
CARM1 Q86X55 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
PRMT8 Q9NR22 1/20 0.36
ATM Q13315 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
CHRM5 P08912 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19506632 0.84 HRH3 (0.35) HRH3TSHRALDH1A1
SCHEMBL9621298 0.82 MEN1 (0.36) ATMHRH3TDP1TSHRALDH1A1
SCHEMBL11501574 0.81 LMNA (0.36) LMNACARM1PRMT6PRMT8ATM
SCHEMBL736306 0.81 LMNA (0.36) LMNACARM1PRMT6PRMT8ATM
SCHEMBL20332371 0.80 ALDH1A1 (0.33) LMNAATMHRH3TDP1TSHR
SCHEMBL24891399 0.79 HRH3 (0.39) LMNACARM1PRMT6PRMT8ATM
SCHEMBL3630893 0.79 HRH3 (0.39) LMNACARM1PRMT6PRMT8ATM
SCHEMBL22342735 0.79 HRH3 (0.39) LMNACARM1PRMT6PRMT8ATM
SCHEMBL135698 0.79 HRH3 (0.39) LMNACARM1PRMT6PRMT8ATM
SCHEMBL12108497 0.79 LMNA (0.35) LMNACARM1PRMT6PRMT8ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3124490-A1 HIGH STABILITY POLYIONIC LIQUID SALTS Sigma-Aldrich Co. LLC (US) 2017-02-01 EP disclosed
US-8481722-B2 High stability polyionic liquid salts SIGMA-ALDRICH CO. LLC (US) 2013-07-09 US disclosed
US-20120083603-A1 HIGH STABILITY POLYIONIC LIQUID SALTS SIGMA-ALDRICH CO. LLC (US) 2012-04-05 US disclosed
US-8097721-B2 polycationic or polyanionic molecules; use as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS); thermal stability; tris(anion) such as tris(sulfonate) or tris(cation) groups such as imidazolium, pyrrolidinium, ammonium SIGMA-ALDRICH CO. LLC (US) 2012-01-17 US disclosed
US-20080210858-A1 High Stability Polyionic Liquid Salts SIGMA-ALDRICH CO. NEWCO INC. 2008-09-04 US disclosed
WO-2008095069-A2 HIGH STABILITY POLYIONIC LIQUID SALTS SIGMA-ALDRICH CO. (US) 2008-08-07 WO disclosed
US-4156603-A COMPLEXED WITH A POLYFUNCTIONAL LEWIS BASE EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-29 US disclosed
US-4152401-A Chelated lithium aluminum compounds EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-01 US disclosed
US-4147530-A Reductions of inorganic substrates with chelated sodium hydridoaluminates or hydridoborates EXXON RESEARCH & ENGINEERING CO. (US) 1979-04-03 US disclosed
US-4094876-A OIL AND FUEL ADDITIVES EXXON RESEARCH & ENGINEERING CO. (US) 1978-06-13 US disclosed
US-4088666-A Reductions with chelated lithium hydridoaluminates or hydridoborates EXXON RESEARCH & ENGINEERING CO. (US) 1978-05-09 US disclosed
US-3933879-A SEPARATIONS, CATALYTIC REACTIONS, REDUCTIONS, ELECTROCHEMISTRY EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080210858-A1 High Stability Polyionic Liquid Salts PUF60, POLI, PARG LMNA 807/4885CARM1 3871/4885PRMT6 4403/4885
US-20120083603-A1 HIGH STABILITY POLYIONIC LIQUID SALTS PUF60, POLI, PARG LMNA 807/4885CARM1 3871/4885PRMT6 4403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.