SCHEMBL10058697

SCHEMBL10058697

C1CCN2CCCCC2=NC1

nearest known ligand 0.91

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INMT O95050 4/20 0.86
USP2 O75604 2/20 0.86
NOS3 P29474 5/20 0.39
NOS1 P29475 5/20 0.39
NOS2 P35228 5/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SIGMAR1 Q99720 2/20 0.38
ACHE P22303 4/20 0.36
HRH1 P35367 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL496207 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL6038391 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL6859113 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL219036 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL3270217 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2956216 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2742282 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL5475300 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL20718625 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2952223 0.98 INMT (0.91) INMTUSP2NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023214577-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION 中外製薬株式会社 2023-11-09 WO disclosed
EP-4242219-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-13 EP disclosed
WO-2022097540-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION 中外製薬株式会社 2022-05-12 WO disclosed
US-20210226142-A1 UV CROSSLINKING OF PVDF-BASED POLYMERS FOR GATE DIELECTRIC INSULATORS OF ORGANIC THIN-FILM TRANSISTORS CORNING INCORPORATED 2021-07-22 US disclosed
US-20210135109-A1 ACCELERATED THERMAL CROSSLINKING OF PVDF-HFP VIA ADDITION OF ORGANIC BASES, AND THE USAGE OF CROSSLINKED PVDF-HFP AS GATE DIELECTRIC MATERIAL FOR OTFT DEVICES CORNING INCORPORATED 2021-05-06 US disclosed
EP-3452465-B1 SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES GENOSCIENCE PHARMA (FR) 2020-11-04 EP disclosed
US-20190224190-A1 PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-07-25 US disclosed
EP-2439070-B1 Infrared-sensitive positive-working image forming material, planographic printing plate precursor, and method for manufacturing a planographic printing plate FUJIFILM CORP (JP) 2019-07-17 EP disclosed
US-10338469-B2 Photosensitive resin composition, lithographic printing plate precursor and method for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10307414-B2 Pyridinyl and fused pyridinyl triazolone derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-06-04 US disclosed
US-8097721-B2 polycationic or polyanionic molecules; use as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS); thermal stability; tris(anion) such as tris(sulfonate) or tris(cation) groups such as imidazolium, pyrrolidinium, ammonium SIGMA-ALDRICH CO. LLC (US) 2012-01-17 US disclosed
EP-1251395-B1 Silver halide photographic material containing a methine dye FUJIFILM CORP (JP) 2010-09-29 EP disclosed
US-20080210858-A1 High Stability Polyionic Liquid Salts SIGMA-ALDRICH CO. NEWCO INC. 2008-09-04 US disclosed
US-20080210858-A1 High Stability Polyionic Liquid Salts SIGMA-ALDRICH CO. NEWCO INC. 2008-09-04 US disclosed
WO-2008095069-A2 HIGH STABILITY POLYIONIC LIQUID SALTS SIGMA-ALDRICH CO. (US) 2008-08-07 WO disclosed
US-7291449-B2 Silver halide photographic material and methine dye FUJIFILM CORPORATION (JP) 2007-11-06 US disclosed
US-7232640-B1 Positive resist composition FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7232640-B1 Positive resist composition FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-20070128547-A1 POSITIVE RESIST COMPOSITION FUJI PHOTO FILM CO., LTD. 2007-06-07 US disclosed
US-20070128547-A1 POSITIVE RESIST COMPOSITION FUJI PHOTO FILM CO., LTD. 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080210858-A1 High Stability Polyionic Liquid Salts PUF60, POLI, PARG INMT 3268/4885USP2 1630/4885NOS3 4477/4885
US-20190224190-A1 PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES BTK, LCK, TYK2 INMT 2238/4885USP2 3732/4885NOS3 1117/4885
US-10307414-B2 Pyridinyl and fused pyridinyl triazolone derivatives BTK, LCK, TYK2 INMT 2238/4885USP2 3732/4885NOS3 1117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.