SCHEMBL496207

SCHEMBL496207

C1CCC2=NCCCCN2CC1

nearest known ligand 0.91

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
INMT O95050 4/20 0.91
USP2 O75604 2/20 0.91
NOS3 P29474 5/20 0.41
NOS1 P29475 5/20 0.41
NOS2 P35228 5/20 0.41
ACHE P22303 5/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219036 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL6859113 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL5475300 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2956216 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL3270217 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2956214 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL6038391 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2742282 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL20718625 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2
SCHEMBL2952223 1.00 INMT (0.91) INMTUSP2NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
WO-2023153508-A1 NOVEL DIHYDROOXAPHOSPHAPHENANTHRENE DERIVATIVE HAVING TRIAZINE RING AND EXHIBITING HIGH REFRACTIVE INDEX, AND METHOD FOR PRODUCING SAME 三光株式会社 2023-08-17 WO disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-06 US disclosed
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-01-06 US disclosed
EP-3892610-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT The Scripps Research Institute (US) 2021-10-13 EP disclosed
US-11141385-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2021-10-12 US disclosed
US-20210226142-A1 UV CROSSLINKING OF PVDF-BASED POLYMERS FOR GATE DIELECTRIC INSULATORS OF ORGANIC THIN-FILM TRANSISTORS CORNING INCORPORATED 2021-07-22 US disclosed
US-20210135109-A1 ACCELERATED THERMAL CROSSLINKING OF PVDF-HFP VIA ADDITION OF ORGANIC BASES, AND THE USAGE OF CROSSLINKED PVDF-HFP AS GATE DIELECTRIC MATERIAL FOR OTFT DEVICES CORNING INCORPORATED 2021-05-06 US disclosed
EP-3151817-B1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF SCRIPPS RESEARCH INST (US) 2021-03-03 EP disclosed
EP-0934925-A1 Process for the preparation of beta-alkoxy nitriles BASF AKTIENGESELLSCHAFT (DE) 1999-08-11 EP disclosed
EP-0919555-A1 Process for the preparation of bicyclic amidines, diazacycloalkenes and a process for their preparation BASF AKTIENGESELLSCHAFT (DE) 1999-06-02 EP disclosed
EP-0915888-A1 FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS Takeda Chemical Industries, Ltd. (JP) 1999-05-19 EP disclosed
WO-1998054197-A1 MULTICYCLIC ERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 1998-12-03 WO disclosed
WO-1998030720-A1 BIOCONJUGATION OF OLIGONUCLEOTIDES PROLIGO LLC (US) 1998-07-16 WO disclosed
WO-1997040051-A1 FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-30 WO disclosed
US-5032167-A Herbicides BASF (DE) 1991-07-16 US disclosed
US-4943633-A Catalytic preparation of cyanoalkyl lactams AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-07-24 US disclosed
US-4857100-A Phenylsulfonylureas CIBA-GEIGY CORPORATION (US) 1989-08-15 US disclosed
US-4759792-A Herbicide and plant growth regulator CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF QSOX1, YBX1, SFXN1 INMT 788/4885USP2 2177/4885NOS3 1506/4885
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF PTMS, IGF2R, SCTR INMT 1676/4885USP2 4140/4885NOS3 3404/4885
US-11141385-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof CYP2F1, CYP2S1, NAF1 INMT 2235/4885USP2 3552/4885NOS3 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.