SCHEMBL1005901

SCHEMBL1005901

CCCc1ccc(CCC)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.61
CNR2 P34972 1/20 0.61
ALOX5 P09917 3/20 0.56
TYR P14679 3/20 0.52
CYP3A4 P08684 2/20 0.48
TSHR P16473 2/20 0.48
MEN1 O00255 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
ALOX15 P16050 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
CYP2D6 P10635 1/20 0.47
DRD2 P14416 1/20 0.47
NFKB1 P19838 1/20 0.47
DRD1 P21728 1/20 0.47
DRD4 P21917 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5167885 0.90 TYR (0.67) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL5168590 0.90 TYR (0.61) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL5167232 0.89 TRPA1 (0.59) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL50708 0.89 CNR1 (0.59) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL5168102 0.89 CNR1 (0.59) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL6561766 0.88 BACE1 (0.61) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL10666157 0.84 MAPT (0.51) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL10666145 0.84 ALOX15 (0.51) CNR1CNR2ALOX5TYRCYP3A4
SCHEMBL83606 0.83 TYR (0.69) ALOX5TYRCYP3A4TSHRMEN1
SCHEMBL5164462 0.83 GABRA1 (0.58) CNR1CNR2ALOX5TYRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
CN-120118458-A Curable composition, resin, and cured product 东京应化工业株式会社 2025-06-10 CN disclosed
CN-119937242-A Photosensitive resin composition 东京应化工业株式会社 2025-05-06 CN disclosed
CN-114514261-B Polyphenylene ether composition 旭化成株式会社 2024-09-10 CN disclosed
CN-117327362-A Curable resin composition 东京应化工业株式会社 2024-01-02 CN disclosed
CN-117229495-A Polyphenylene ether, method for producing the same, thermosetting composition, prepreg, and laminate 旭化成株式会社 2023-12-15 CN disclosed
CN-117215149-A Photosensitive resin composition 东京应化工业株式会社 2023-12-12 CN disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
CN-112812291-B Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2023-07-18 CN disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
US-6884814-B2 Phenyl benzisoxazoles as estrogenic agents WYETH (US) 2005-04-26 US disclosed
US-6841650-B2 Crystallizable poly (2,5-di-substituted-1,4-phenylene oxide) and a method of preparing the same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2005-01-11 US disclosed
WO-2004108642-A1 METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS BASF AKTIENGESELLSCHAFT (DE) 2004-12-16 WO disclosed
WO-2004069779-A1 METHOD FOR PRODUCING 2,2'-DIHYDROXYBIPHENYLS BASF AKTIENGESELLSCHAFT (DE) 2004-08-19 WO disclosed
EP-1029882-B1 A crystallizable poly(2,5-di-substituted-1, 4-phenylene oxide) and a method of preparing the same NAT INST OF ADVANCED IND SCIEN (JP) 2004-05-12 EP disclosed
US-20030207927-A1 Phenyl benzisoxazoles as estrogenic agents WYETH 2003-11-06 US disclosed
US-6541596-B1 Subjecting a 2,5-di- substituted phenol to oxidative polymerization in the presence of oxygen and a copper complex catalyst composed of tridentate ligand of which nitrogen atoms are coordiante to a copper atom SECRETARY OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY 2003-04-01 US disclosed
US-20020183475-A1 Crystallizable poly (2,5-di-substituted-1,4-phenylene oxide) and a method of preparing the same SECRETARY OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY 2002-12-05 US disclosed
EP-1029882-A2 A crystallizable poly(2,5-di-substituted-1, 4-phenylene oxide) and a method of preparing the same Secretary of Agency of Industrial Science and Technology (JP) 2000-08-23 EP disclosed
US-4360469-A Preparation of quinones by salcomine-catalyzed oxidation of phenols EASTMAN KODAK COMPANY (US) 1982-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207927-A1 Phenyl benzisoxazoles as estrogenic agents ESR1, ESR2, GPER1 CNR1 194/4885CNR2 370/4885ALOX5 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.