SCHEMBL10059283

SCHEMBL10059283

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6oc7ccccc7c6c5)ccc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 1/20 0.36
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PLA2G10 O15496 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGER4 P35408 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18842393 0.98 L3MBTL1 (0.36) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL9881132 0.97 CHEK2 (0.35) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL12088880 0.97 CHEK2 (0.35) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL24216513 0.97 PLA2G2A (0.36) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL15786068 0.97 CHEK2 (0.38) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL22257642 0.97 CHEK2 (0.38) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL15786123 0.97 CHEK2 (0.38) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL12088485 0.96 PLA2G2A (0.38) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL15786110 0.95 KDM4E (0.39) CHEK2PLA2G2APLA2G4ARAC2RAC3
SCHEMBL16943298 0.95 PLA2G2A (0.39) CHEK2PLA2G2APLA2G4ARAC2RAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-07-07 US disclosed
US-11316113-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-04-26 US disclosed
US-20210184119-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-06-17 US disclosed
US-20190081246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-14 US disclosed
US-9954180-B2 Bicarbazole compounds for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2018-04-24 US disclosed
US-9954180-B2 Bicarbazole compounds for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2018-04-24 US disclosed
US-20170170409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-15 US disclosed
US-20170170409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-15 US disclosed
US-20170155049-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
US-20170155049-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
US-20140131665-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20140131665-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20130140549-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-06-06 US disclosed
US-20130140549-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-06-06 US disclosed
WO-2012023947-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYMS, UMPS, TYMP CHEK2 271/4885PLA2G2A 4841/4885PLA2G4A 4856/4885
US-11316113-B2 Organic electroluminescent materials and devices TYMS, UMPS, TYMP CHEK2 271/4885PLA2G2A 4841/4885PLA2G4A 4856/4885
US-20190081246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYMS, UMPS, TYMP CHEK2 271/4885PLA2G2A 4841/4885PLA2G4A 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.