Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1006310 | 0.99 | HTR3A (0.46) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1006151 | 0.85 | HTR3A (0.64) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1007234 | 0.84 | HTR3A (0.64) | HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL1005255 | 0.83 | HTR3A (0.63) | HTR3AKCNH2 | |
| SCHEMBL3990688 | 0.82 | HTR3A (0.46) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1005962 | 0.79 | HTR3A (0.74) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1005964 | 0.79 | HTR3A (0.74) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1006334 | 0.79 | HTR3A (0.42) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1006311 | 0.78 | HTR3A (0.72) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1006308 | 0.78 | HTR3A (0.72) | HTR3AKCNH2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863271-B2 | 2-aminobenzoxazole carboxamides as 5HT3 modulators | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | AMR TECHNOLOGY, INC. (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | HTR3E, HTR3C, HTR3A | HTR3A 3/4885KCNH2 1871/4885ALDH1A1 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.