Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL899669 | 0.72 | TSHR (0.48) | — | |
| Biphenyl SCHEMBL28193720 | 0.72 | ALDH1A1 (0.43) | — | |
| Toluene SCHEMBL28188524 | 0.71 | TSHR (0.46) | — | |
| Benzene SCHEMBL9464137 | 0.71 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL17092521 | 0.70 | APP (0.34) | — | |
| Toluene SCHEMBL5492947 | 0.69 | TSHR (0.44) | — | |
| Chlorobenzene SCHEMBL27446491 | 0.69 | TSHR (0.48) | — | |
| SCHEMBL3941832 | 0.69 | CYP3A4 (0.52) | — | |
| SCHEMBL15953455 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL27467670 | 0.68 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803761-B1 | Ring-opened copolymer, hydrogenated ring-opened copolymer, process for producing thereof, and compositions | ZEON CORP (JP) | 2016-04-27 | — | — | EP | disclosed |
| EP-2270063-B1 | PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION | ZEON CORP (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-1197509-B1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | ZEON CORP (JP) | 2011-07-06 | — | — | EP | disclosed |
| EP-2270063-A2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | NIPPON ZEON CO., LTD. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-7820355-B2 | Radiation sensitive resin composition | ZEON CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| EP-1408064-B1 | OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS | ZEON CORP (JP) | 2008-07-30 | — | — | EP | disclosed |
| EP-1803761-A1 | Ring-opened copolymer, hydrogenated ring-opened copolymer, process for producing thereof, and compositions | ZEON CORPORATION (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20060040201-A1 | Radiation sensitive resin composition | ZEON CORPORATION (JP) | 2006-02-23 | — | — | US | disclosed |
| US-6995226-B2 | Open-ring copolymer, hydrogenated open-ring copolymer, process for production of both, and compositions | ZEON CORPORATION (JP) | 2006-02-07 | — | — | US | disclosed |
| US-6908970-B2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION (JP) | 2005-06-21 | — | — | US | disclosed |
| US-20040152843-A1 | Open-ring copolymer, hydrogenated open-ring copolymer, process for production of both, and compositions | ZEON CORPORATION (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1408064-A1 | OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS | Zeon Corporation (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-20030050406-A1 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION | 2003-03-13 | — | — | US | disclosed |
| US-6486264-B1 | Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin | ZEON CORPORATION (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1197509-A1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | Nippon Zeon Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |