Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937862 | 0.91 | CYP3A4 (0.43) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| SCHEMBL23812215 | 0.86 | SLC18A3 (0.39) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Benzene SCHEMBL9464137 | 0.81 | KDM4E (0.30) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21606905 | 0.79 | KMO (0.38) | CYP3A4TDP1SLC18A3 | |
| SCHEMBL8784921 | 0.78 | CYP3A4 (0.52) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Toluene SCHEMBL899669 | 0.78 | TSHR (0.48) | CYP3A4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL301069 | 0.77 | CYP3A4 (0.38) | CYP3A4TDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL54719 | 0.77 | ROCK2 (0.44) | CYP3A4TDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL301129 | 0.77 | ROCK2 (0.44) | CYP3A4TDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL13456274 | 0.77 | CYP3A4 (0.38) | CYP3A4TDP1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110290872-A | Method for producing catalyst liquid | 株式会社可乐丽 | 2019-09-27 | — | — | CN | disclosed |
| CN-107179652-A | Positive photosensitive polysiloxane composition and application thereof | 奇美实业股份有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-103153462-A | Hydroformylation process | DOW TECHNOLOGY INVESTMENTS LLC | 2013-06-12 | — | — | CN | disclosed |
| US-20090326229-A1 | ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF | TAKEDA PHAMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2049535-A1 | ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008016184-A1 | ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-07 | — | — | WO | disclosed |
| EP-0696568-B1 | Process for preparing substituted 4-methylidene cinnamic acid derivatives as well as novel methylidene cinnamic acid derivatives | MERCK PATENT GMBH (DE) | 2000-05-10 | — | — | EP | disclosed |
| EP-0696568-A1 | Process for preparing substituted 4-methylidene cinnamic acid derivatives as well as novel methylidene cinnamic acid derivatives | MERCK PATENT GmbH (DE) | 1996-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326229-A1 | ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF | XDH, F7, CYP4X1 | CYP3A4 116/4885TDP1 3025/4885ESR1 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.