Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | MDH1 | P40925 | 1/20 | 0.33 |
| ▸ | MDH2 | P40926 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060123 | 0.94 | MAPT (0.46) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL15943550 | 0.90 | MAPT (0.45) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL10060125 | 0.80 | KDM4E (0.43) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL15338095 | 0.78 | MAPT (0.61) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL10060119 | 0.78 | POLB (0.49) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL12299537 | 0.77 | MAPT (0.47) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL13707248 | 0.77 | GFER (0.51) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL10060207 | 0.73 | MAPT (0.47) | MAPTKDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL15943553 | 0.73 | ALDH1A1 (0.33) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL764915 | 0.72 | MAPT (0.44) | MAPTKDM4ERAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904583-B1 | PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. | AGFA GRAPHICS NV (BE) | 2012-03-21 | — | — | EP | disclosed |