SCHEMBL10060119

SCHEMBL10060119

COC(=O)c1cc(N/N=C(/C(C)=O)C(=O)Nc2ccccc2OCCO)cc(C(=O)OC)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.49
HPGD P15428 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAPT P10636 8/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 2/20 0.43
KMT2A Q03164 6/20 0.43
RAB9A P51151 4/20 0.43
MEN1 O00255 3/20 0.43
TDP1 Q9NUW8 2/20 0.41
CASP6 P55212 1/20 0.41
CREBBP Q92793 1/20 0.39
NPC1 O15118 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KCNH2 Q12809 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15943552 0.86 MAPT (0.49) POLBNPSR1MAPTALDH1A1MAPK1
SCHEMBL764899 0.85 ALDH1A1 (0.49) POLBHPGDMAPTALDH1A1MAPK1
SCHEMBL12998588 0.84 MAPT (0.55) POLBMAPTALDH1A1MAPK1KMT2A
SCHEMBL765365 0.84 MAPT (0.55) POLBMAPTALDH1A1MAPK1KMT2A
SCHEMBL10060123 0.82 MAPT (0.46) POLBMAPTALDH1A1MAPK1KMT2A
SCHEMBL13679873 0.82 ALDH1A1 (0.42) POLBHPGDNPSR1MAPTALDH1A1
SCHEMBL10060201 0.82 POLB (0.43) POLBHPGDNPSR1MAPTALDH1A1
SCHEMBL15943537 0.81 ALDH1A1 (0.43) POLBHPGDMAPTALDH1A1MAPK1
SCHEMBL10060120 0.80 NPC1 (0.51) POLBHPGDNPSR1MAPTALDH1A1
SCHEMBL13707248 0.79 GFER (0.51) POLBHPGDNPSR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904582-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2014-08-13 EP disclosed
EP-1904585-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-23 EP disclosed
EP-1904580-B1 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-16 EP disclosed
EP-1904583-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2012-03-21 EP disclosed
US-7582152-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582151-B2 Pigment dispersion with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582152-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582151-B2 Pigment dispersion with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-20090005474-A1 Pigment Dispersions With Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2009-01-01 US disclosed
US-20090005474-A1 Pigment Dispersions With Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2009-01-01 US disclosed
US-20080242776-A1 Pigment Dispersion with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-10-02 US disclosed
US-20080242776-A1 Pigment Dispersion with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-10-02 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed