Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060119 | 0.82 | POLB (0.49) | POLBHPGDNPSR1TDP1CASP6 | |
| SCHEMBL764899 | 0.78 | ALDH1A1 (0.49) | POLBHPGDTDP1CASP6KMT2A | |
| SCHEMBL12998588 | 0.74 | MAPT (0.55) | POLBTDP1CASP6KMT2AMAPT | |
| SCHEMBL765365 | 0.74 | MAPT (0.55) | POLBTDP1CASP6KMT2AMAPT | |
| SCHEMBL13679873 | 0.73 | ALDH1A1 (0.42) | POLBHPGDNPSR1TDP1CASP6 | |
| SCHEMBL15943552 | 0.72 | MAPT (0.49) | POLBNPSR1TDP1CASP6KMT2A | |
| SCHEMBL14626257 | 0.72 | KMT2A (0.46) | POLBTDP1CASP6KMT2AMAPT | |
| SCHEMBL15943537 | 0.71 | ALDH1A1 (0.43) | POLBHPGDTDP1CASP6KMT2A | |
| SCHEMBL10060120 | 0.70 | NPC1 (0.51) | POLBHPGDNPSR1TDP1CASP6 | |
| SCHEMBL15338086 | 0.70 | ALDH1A1 (0.48) | POLBHPGDNPSR1TDP1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904583-B1 | PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. | AGFA GRAPHICS NV (BE) | 2012-03-21 | — | — | EP | disclosed |