SCHEMBL765365

SCHEMBL765365

COc1ccccc1NC(=O)/C(=N\Nc1ccccc1OCCO)C(C)=O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
ALDH1A1 P00352 3/20 0.55
MAPK1 P28482 1/20 0.55
TDP1 Q9NUW8 2/20 0.52
POLB P06746 1/20 0.52
CASP6 P55212 1/20 0.52
RAB9A P51151 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KMT2A Q03164 5/20 0.43
KCNH2 Q12809 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.42
MLYCD O95822 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12998588 1.00 MAPT (0.55) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL15943537 0.90 ALDH1A1 (0.43) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL764920 0.89 MAPT (0.49) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL10060120 0.89 NPC1 (0.51) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL15943552 0.88 MAPT (0.49) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL764924 0.88 ALDH1A1 (0.44) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL10060616 0.87 MAPT (0.48) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL765695 0.86 GAA (0.52) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL12998590 0.84 MAPT (0.48) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL12998511 0.84 MAPT (0.48) MAPTALDH1A1MAPK1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904582-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2014-08-13 EP disclosed
EP-1904585-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-23 EP disclosed
EP-1904580-B1 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-16 EP disclosed
EP-1904581-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-04-10 EP disclosed
EP-1904583-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2012-03-21 EP disclosed
US-7846992-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2010-12-07 US disclosed
US-7846992-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2010-12-07 US disclosed
US-7812113-B2 Phenylazo-acetoacetanilide derivatives with a polymerizable functional group and related compounds as monomers for preparing polymeric pigment dispersants for inkjet inks AGFA GRAPHICS NV (BE) 2010-10-12 US disclosed
US-7812113-B2 Phenylazo-acetoacetanilide derivatives with a polymerizable functional group and related compounds as monomers for preparing polymeric pigment dispersants for inkjet inks AGFA GRAPHICS NV (BE) 2010-10-12 US disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080214705-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-04 US disclosed
US-20080214705-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-04 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed
US-20080177016-A1 Phenylazo-Acetoacetanilide Derivatives with a Polymerizable Functional Group and Related Compounds as Monomers for Preparing Polymeric Pigment Dispersants for Inkjet Inks AGFA GRAPHICS NV (BE) 2008-07-24 US disclosed
US-20080177016-A1 Phenylazo-Acetoacetanilide Derivatives with a Polymerizable Functional Group and Related Compounds as Monomers for Preparing Polymeric Pigment Dispersants for Inkjet Inks AGFA GRAPHICS NV (BE) 2008-07-24 US disclosed
WO-2007006637-A2 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2007-01-18 WO disclosed
WO-2007006682-A1 PHENYLAZO-ACETOACETANILIDE DERIVATIVES WITH A POLYMER! ZABLE FUNCTIONAL GROUP AND RELATED COMPOUNDS AS MONOMERS FOR PREPARING POLYMERIC PIGMENT DISPERSANTS FOR INKJET INKS AGFA GRAPHICS NV (BE) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177016-A1 Phenylazo-Acetoacetanilide Derivatives with a Polymerizable Functional Group and Related Compounds as Monomers for Preparing Polymeric Pigment Dispersants for Inkjet Inks RB1, TYR, AKR1D1 MAPT 346/4885ALDH1A1 12/4885MAPK1 367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.