Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.43 |
| ▸ | SCN1A | P35498 | 5/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005490 | 0.92 | SYK (0.43) | UTS2RSCN1ASCN8AGPR119 | |
| SCHEMBL1006057 | 0.92 | SCN1A (0.43) | UTS2RSCN1ASCN8A | |
| SCHEMBL1005830 | 0.91 | DGAT2 (0.43) | UTS2RSCN1ASCN8AGPR119 | |
| SCHEMBL1006626 | 0.90 | GPR119 (0.50) | SCN1ASCN8AGPR119KCNH2 | |
| SCHEMBL1005953 | 0.89 | DGAT2 (0.46) | UTS2RKCNH2 | |
| SCHEMBL1008624 | 0.89 | GPR119 (0.47) | UTS2RSCN1ASCN8AGPR119 | |
| SCHEMBL1003873 | 0.89 | SCN8A (0.44) | SCN1ASCN8AGPR119KCNH2 | |
| SCHEMBL12239164 | 0.88 | HRH1 (0.44) | UTS2RHRH1CCR3KCNH2 | |
| SCHEMBL1005438 | 0.88 | SCN8A (0.47) | SCN1ASCN8A | |
| SCHEMBL1006218 | 0.86 | UTS2R (0.46) | UTS2RSCN1ASCN8AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
| EP-2271619-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | UTS2R 265/4885SCN1A 1881/4885SCN8A 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.